Unexplained male infertility: diagnosis and management.
نویسندگان
چکیده
Unexplained male infertility is a diagnosis reserved for men in whom routine semen analyses results are within normal values and physical as well as endocrine abnormalities were ruled out. In addition to erectile problems and coital factors, immunologic causes and sperm dysfunction may contribute to such condition. New etiologies of unexplained male infertility include low level leukocytospermia and mitochondrial DNA polymerase gene polymorphism. Contemporary andrology may reveal cellular and sub-cellular sperm dysfunctions which may explain subfertility in such cases, thus aiding the clinician to direct the further work-up, diagnosis and counseling of the infertile male. The objective of this article is to highlight the concept of unexplained male infertility and focuses on the diagnosis and treatment of this condition in the era of modern andrology and assisted reproductive techniques. Extensive literature review was performed using the search engines: Pubmed, Science-direct, Ovid and Scopus.
منابع مشابه
Unexplained male infertility: potential causes and management
Human Andrology 2011, 1:2–16 Objective To highlight the concept of unexplained male infertility and discuss the potential causes and its proper management. Design Review of literature. Results Male infertility of unknown origin is a condition in which fertility impairment occurs spontaneously or due to an obscure or unknown cause. It includes two categories, unexplained male infertility and idi...
متن کاملThe Role of Contemporary Andrology in Unraveling the Mystery of Unexplained Male Infertility
Unexplained male infertility is a condition in which infertile men have normal semen analyses on multiple occasions with no obvious physical or endocrine abnormality when female partner infertility has been ruled out. In addition to erectile problems and coital factors, immune causes and dysfunctional sperm may contribute to such condition. Contemporary andrology may help analyze the unexplaine...
متن کاملI-5: Alteration in ?-Defensin 126 Genes Associated with Unexplained Male Infertility and ART Outcomes
متن کامل
Unexplained Male Infertility – Looking Beyond Routine Semen Analysis
Unexplained infertility is a diagnosis reserved for couples in whom routine semen analysis is within normal values and female infertility factors have been ruled out. Its reported prevalence ranges from 6–27 % depending on how exhaustive the patient work-up is. Despite differing according to urological societies, recommendation for male infertility evaluation usually considers routine semen ana...
متن کاملKisspeptin, unexplained infertility and embryo implantation
Objective The primary objective of the study was to compare baseline KP levels in females with different causes of infertility and then correlate it with the risk of failure to conceive, preclinical abortion and pregnancy after intracytoplasmic sperm injection (ICSI). MaterialsAndMethods AA longitudinal cohort study was carried out from August 2014 till May 2015 recruiting one hundred and twent...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- International braz j urol : official journal of the Brazilian Society of Urology
دوره 38 5 شماره
صفحات -
تاریخ انتشار 2012